krsma
Forum Elite
Topics: 40
Posts: 227
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1. Give the mechanism of action
2. Therapeutic uses?
3. what are the side effects?
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| Bela
Forum Guru
Topics: 76
Posts: 412
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Gemfibrozil increases the activity of Lipoprotein Lipase in the Adipose Tissue and causes VLDL clearance from the blood stream.
Indications: hypertriglyceridemia (VLDL predominates)
Side Effects: Skin rash; rhabdomyolysis (when used w/HMG CoA reductase inhibitors)
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La vita e bella!
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| krsma
Forum Elite
Topics: 40
Posts: 227
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u're right Bela,
also just to add:
it's not useful in type 1 hyperlipidemia
-useful in treating types 3, 4, and 5 hyperlipidemia
SE can also include gall stones along w/ ones mentioned above.
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