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Kaplan Qbank USMLE



Author6 Posts
  #1

Renal correction of hyperkalemia will result in which of the following?
A.
Alkalosis
B.
Acidosis
C.
Increased secretion of HCO3–
D.
Increased secretion of H+
E.
Increased excretion of Na+


the answer is.....but why ? you may think about the opposite situation before answering this and get to the same result ! i am quite confused sad

  #2

HMM, i wud say renal correction wud result in acidosis, if ur thinking only in terms kidney.
here priority becomes to loose k+.
the resiratory correction is set at a level to correct extra h+ in the extra cellular fluid and that conserved by kidney.

  #3

Addison's dz --> Decreased aldostrone--->HyprKalemia , Metabolic acidosis

Hyperkalemia----> INCREASED aldostrone ---> metablic acidosis


K+ sparing diuretics ----> Decreased aldostrone---> Hyper kalemia , Metabolic acidosis.


( Conn's dz )----> incresed Aldostrone ---> HYPO kalemia , metabolic alkalosis,

how could Decreased and Increased of Aldostron ends to same result ?

or how could Increased Aldostrone ends to both acidosis and alkalosis ?
:-?

  #4

oh bro increased aldosteron does not cuz acidosis, it's seen in acidosis.
where it plays part in correction of hyperkalemia.
take a look at ur comment above , in conn's u say that there is hyperaldosteronism, this the primary defect which leads to hypokalemia.
this clarifies that increased aldosteton DOES NOT CAUSE acidosis.
there is diff when u say some thing causes this effect and something is seen in a particular physiological abnormality.

  #5

there are many things in physiology where u wud see diff effects by same agent depending on it's concentration.
e.g. hypervitaminosis D or hypovit. D will result in osteoporosis.
like wise u may find increased or decreased levels of aldosteron in acidosis, u have to know what is the primary insult and then the bodies defense mechanisms that too on a priority basis!!

  #6

thanks buddy .

smiling face








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