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webpath13

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4 Posts

po
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Topics: 39
Posts: 356

07/20/07 - 11:24 AM

A 35-year-old man has noted several 1 to 2 cm reddish purple, nodular lesions present on the skin of his right arm which have increased in size and number over the past 3 months. The lesions do not itch and are not painful. He has had a watery diarrhea for the past month. On physical examination he has generalized lymphadenopathy and oral thrush. Which of the following infections is most likely to be related to the appearance of these skin lesions?

A Candida albicans

B Human herpesvirus 8

C Mycobacterium tuberculosis

D Pseudomonas aeruginosa

E Pneumocystis carinii (jiroveci)

SmokyWaters
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Topics: 6
Posts: 458

07/20/07 - 11:25 AM

B ???

SmokyWaters
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Topics: 6
Posts: 458

07/20/07 - 11:26 AM

well answered it by ruling out the other causes... :$ ....which I consider a shameful way to answer....too bad for me

po
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Topics: 39
Posts: 356

07/20/07 - 01:32 PM

SmokyWaters wrote:
well answered it by ruling out the other causes... :$ ....which I consider a shameful way to answer....too bad for me

u r in better position than me,I choseE Pneumocystis carinii (jiroveci) sad

remembered later that I had read this.(B) CORRECT. These plaque-like reddish lesions are characteristic for Kaposi sarcoma. HHV8 (KSHV) is the agent that promotes angiogenesis from which the KS arises in persons with HIV infection.

(E) Incorrect. Pneumocystis carinii (jirovecii) can be seen in persons with AIDS, but it is not related to the AIDS-associated malignancies.
(D) Incorrect. Bacterial infections do not predispose to neoplasia, but persons with neoplasms may have more infections.
(C) Incorrect. Mycobacterial infections are not related to malignancies.
(A) Incorrect. Candida infection is not a risk for malignancy, but persons with malignancies treated with chemotherapy are more likely to get candidal infections.

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