doyoudig
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Could someomne pls explain the differences, their pathophysiology and extracellular/intracellular volume differences btw them and why?
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| doyoudig
Forum Guru
Topics: 144
Posts: 613
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anyone??
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| khorshid
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Cerebral salt wasting:
1.hyponatremia
2.hypovolemia
3.dilute urine, high urinary output
4.high urine NA (>40)
5.follows a brain insult, usually resolves in 1 or 2 weeks, tx:fludrocortisone and fluid repletion
6.high BUN
7.patient thirsty
SIADH:
1.hyponatremia
2.low plasma BUN and UA due to dilution
3.low serum osmolality
4.high urinary NA(>40)
5. low urine ouput
6.patient not thirsty
7. tx:fluid restriction
Basically in CSWS we have dilute urine and natriuresis (both water and NA wasted), in SIADH increased water reabsorption and therefore concentrated urine and hyponatremia due to dilutional effect.
Hope this helps
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| doyoudig
Forum Guru
Topics: 144
Posts: 613
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can u also pls tell me
Intravascular Volume and ECF are increased or decreased for each of them ?
thx much
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| khorshid
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Topics: 32
Posts: 591
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ECF decreased in CSWS and increased in SIADH. (As i said you lose volume plus salt in salt wasting, but you keep volume in SIADH)
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