NSAIDs Q

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NSAIDs Q

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11 Posts

jean robert
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07/15/07 - 02:50 PM

A 42 y.o. patient experiences muscle pain with his daily routine.The pain medication he takes irritates peptic ulcer.He also has a family history of coronary disease.Which of the following is indicated for pain management in this patient?

a.-Aspirin
b.-Celecoxib
c.-Acetaminophen
d.-Indomethacin
e.-Piroxicam

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tompat
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07/15/07 - 11:25 PM

C.
cuz cox 2 and NSAIDs agravate peptic ulcer disease and we can put this pt on dypiridamol or clopidogrel for anti platelet activity.

drhouse
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07/16/07 - 07:28 AM

what about B.

celecoxib have no s/E. of gastric ulcer,,,,,,,

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po
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07/16/07 - 08:47 AM

nope,with family history of coronary disease you dont want to give b.-Celecoxib and get sued

drhouse
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07/16/07 - 11:18 AM

thanks Po,
i forgot it totally.
actually clinical trial says other NSAIDS also increases the risk of heart dis.
so the best choice would be Acetaminophen

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jean robert
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07/16/07 - 01:43 PM

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po
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07/17/07 - 09:38 AM

drhouse wrote:

actually clinical trial says other NSAIDS also increases the risk of heart dis.

but I think in this case you dont give other NSAIDS becoz of peptic ulcer rolling eyes

genes
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08/10/07 - 01:43 PM

but hw acitaminophen??? i does worsen peptic ulcer disease as well as no help fr cornary disease.....???

mikky
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08/13/07 - 10:39 AM

yup... it does not hav antiplatelet action....

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MALUKO
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08/13/07 - 09:57 PM

#10

Acetaminophen is the drug of choice because it works mostly in the cns while in the periphery it's mostly inactivated.

They are not asking for a drug to treat the patient's heart problem rather they are asking for a medication to relieve the patient's pain. so, the other choices should not be considered except for the contraindications due to the patient's family history.

mikky
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08/16/07 - 03:21 AM

#11

oops!!! i didn`t c da q properly.... grin

....thanx

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