From Qs & UW, first line is thyroidectomy as Anti thyroid medications are Contraindicated in preg but in Kaplan, Prop thiouracil is first line as it has less incidence of placental crossing..????
So what is it???
another point missing in Kaplan is that Graves, Mult Scl, PU & Migraine headaches are better in preg, exept for graves may have some effect on the neonate d t crossing of anti thyr abs that will act on the noenates thyroid gland ( Inc thyroid sec)
dr_arc Forum Senior
Topics: 5 Posts: 156
07/15/07 - 05:35 AM
#2
hyperthyroid and pregnant- PTU in first trimester ,surgery in second. both PTU and methimazole cross the placental barrier but PTU considerably less than methimazole , hence preferred in pregnancy.
cirus Forum Guru
Topics: 108 Posts: 740
07/15/07 - 06:42 AM
#3
Got it, appreciate it
thanx.
neuroblastoma Forum Guru
Topics: 103 Posts: 1,046
07/31/07 - 08:05 PM
#4
which antithyroid medication contraindicated --radioactive iodine??right? or else
cirus Forum Guru
Topics: 108 Posts: 740
07/31/07 - 08:08 PM
#5
neuroblastoma wrote: which antithyroid medication contraindicated --radioactive iodine??right? or else
RAI is absolut CI
Methimazole is Absoultely CI
Propylthiouracil is used in 1st trim( less crossin of the placent). 2nd trimest is surgery ( in many cases, thyroid disease improves in preg)..
