asmi
Forum Hero
Topics: 1043
Posts: 4,609
|
Where is the defect in SCIDS ?
|
| Colombia
Forum Guru
Topics: 85
Posts: 438
|
ADA defect
|
| asmi
Forum Hero
Topics: 1043
Posts: 4,609
|
and IL-2 receptor .
|
| Colombia
Forum Guru
Topics: 85
Posts: 438
|
:wink:
|
| usmleasr
Forum Guru
Topics: 105
Posts: 970
|
yeah it can be AR nheritance or X linked.. it affects both B & T cells
|
| usmle2004
Forum Newbie
Topics: 4
Posts: 23
|
Severe combined immunodeficiency syndrome (SCID), a group of immunodeficiencies with major deficiency of both the T cell and B cell functions.
Autosomal recessive SCIDs (T-cell receptor deficiency) and X-linked SCIDs (defect in cytokine recognition by B cell receptors) are two forms. Defects in T-cell enzyme production, both adenosine deaminase and purine nucleoside phosphonylase deficiency, is a third form.
Children present with failure to thrive, infections including pneumocystis carinii pneumonia, candida and CMV infection, affecting skin, lungs, bones and GI tract.
___________________
best,
ed
|
|
| |
| | | | | | |
