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Author8 Posts
  #1

hmm now we have a 26 yr old afro-american with a twin pregnacy, one male and one female fetus.she is now 20 weeks pregnant,what would be the estrogen circulating in mothers blood,type n origin
A.estradiol,from her own ovaries.
B.estradiol, from placenta prepared from her adrenal androgens.
C.estriol, from placenta prepared from female fetus adrenal androgens
D.estriol, from placenta prepared from both fetal adrenal androgens
E.estrdiol, from placenta prepared from mothers cholesterol

  #2

After 6 weeks placenta is producing estrogens.

Ans: D


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Mr. Physiology. An answering machine.

  #3

I know it estriol,[ from placenta prepared from both fetal adrenal androgens ]is basis for making downs diagnosis,but E also seems right which is responsible for maintaining the pregnancyraised eyebrow

  #4

the placenta produces estriol, ovaries estradiol


___________________
Mr. Physiology. An answering machine.

  #5

yes D is the ans.
about estradiol,i think it is mainly secreted by ovary and is resposible until 3 rd month of pregnancy.
then afterward its estriol,from placenta. it's been mentioned in k notes that if u remove both ovaries after 3 months of pregnacy , it continues.

  #6

wow,had not touched kaplan physio;such a huge book compared to all others.

  #7

fetal adrenal lacks 3 beta hydroxysteroid dehydrogenase necessary for conversion of DHEA into testosteron,and also production of gluco n mineralo corticoids is hampered.
DHEA goes to placenta and gets converted to estriol.
correlation:
in DCT cells 11 beta hydroxysteroid dehydrogenase is present which degrades cortisol.
chinese people eat LICORICE a tonic, which inhibits this enzyme, so cortisol goes unchecked and it acts on aldosteron receptors. result is hypertention and hypokalemia.

  #8

yes remember like this

single female--estrone

married---estrdiol

pregnant(mother,father,and baby)---estrtriol


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