Jackofknives
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You cannot access cell density precisely with MRI for usual clinical use, the resolution is just too low.
Edited by Jackofknives on 07/11/07 - 12:24 PM
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| ianosv
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I know you cannot see cells, however Saggital T1 could show more or less space between the terminations, does this mean loss of gray matter? I've searched google and found an example where the atrophy was shown as almost arbor vitae(white matter) only, could this be a pattern?
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| new_n_lost
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Guys Just a thopught Wudnt a hypoplastic cerebellum be presented in a young infant rather than 24 yr old person USMLE wise.
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| Jackofknives
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Yea sure, with MRI you can see by the intensity of the image whether the tissue is normal, atrophied or absent, but this cannot be used for research purposes bc the value is way to crude. E.g. you can't say the density is 1.5*10^5 per mm^3.
new_n_lost yea I suppose they will be presented in the young bc thats how early we can diagnose it.
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| Dr.Papez
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Clinical scenario should help. As NNL pointed out hypoplasia is either incidental finding and may manifest only with delayed walking. Whereas atrophy indicate acquired process where you will see loss of acquired cerebellar function. I guess hypoplasia as is congeital will result in smaller posterior fossa and you may not see marked CSF spaces whereas atrophy will result in prominent CSF spaces. Does that help?
But this discussion is too much for USMLE exam. They will never ask such questions.
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| ianosv
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yes, that helps
and the presence of mega cisterna magna should suggest which case?
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| Dr.Papez
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hypoplasia
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