new_n_lost
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Which of the following drugs used in the treatment of noninsulin-dependent diabetes mellitus (NIDDM) has no effect on the secretion of insulin?
A. Acetohexamide
B. Chlorpropamide
C. Glyburide
D. Metformin
E. Tolbutamide
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| tompat
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d
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| drhouse
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only metformin doesnt increases insulin secrection
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| SILVER
DoWhatYouGotToDo!
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D. Metformin
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| Luckyall
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D
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| new_n_lost
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"never argue with a fool, they'll bring you down to their level and beat you with experience" FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."
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| new_n_lost
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The correct answer is D.
Metformin is a drug that is often used in conjunction with oral hypoglycemic agents for the treatment of NIDDM. Its mechanism of action is two-fold:
(1) it decreases the production of glucose in the liver.
(2) it increases the uptake of glucose in the liver.
Metformin has no effect on the secretion of pancreatic insulin.
Acetohexamide (choice A) is an oral hypoglycemic agent that is a sulfonylurea derivative. It stimulates secretion of insulin from the pancreas.
Chlorpropamide (choice B) is an oral hypoglycemic agent that is a sulfonylurea derivative. It stimulates secretion of insulin from the pancreas.
Glyburide (choice C) is a sulfonylurea derivative that stimulates insulin secretion from the pancreas.
Tolbutamide (choice E) is a sulfonylurea derivative that stimulates insulin secretion from the pancreas.
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"never argue with a fool, they'll bring you down to their level and beat you with experience" FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."
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