new_n_lost
Politically InCorrect
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Which in the following is not an extraintestinal manifestation of inflammatory bowel disease?
a) Aphthous stomatitis
b) Primary sclerosing cholangitis
c) Primary biliary cirrhosis
d) Ankylosing spondylitis
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| drhouse
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C
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everybody can do it.... its just matter of time
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| faraym
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 C?
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| GOGETA
I'm Dr. GOGETA
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a
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As a general rule, the better it felt when you said it, the more trouble it's going to get you into.
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| SmokyWaters
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its primary billiary cirrhosis...
Primary biliary cirrhosis is an autoimmune disease of the liver marked by the slow progressive destruction of the small bile ducts (bile canaliculi) within the liver. the etiology is unknown at the moment but if its PRIMARY then it cant be related to IBD... common sense :P
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| tompat
Forum Elite
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oh bro then why wud primary sclerosing cholangitis?
Edited by tompat on 07/05/07 - 06:52 AM
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| po
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SmokyWaters wrote:
its primary billiary cirrhosis...
Primary biliary cirrhosis is an autoimmune disease of the liver marked by the slow progressive destruction of the small bile ducts (bile canaliculi) within the liver. the etiology is unknown at the moment but if its PRIMARY then it cant be related to IBD... common sense :P
agree.
from
http://www.merck.com/mmpe/sec02/ch018/ch018a.html
Extraintestinal Manifestations
Crohn's disease and UC both affect organs other than the intestines. Most extraintestinal manifestations are more common in UC and Crohn's colitis than in Crohn's disease limited to the small bowel. Extraintestinal manifestations are categorized in three ways:
1. Disorders that usually parallel (ie, wax and wane with) IBD flare-ups. These include peripheral arthritis, episcleritis, aphthous stomatitis, erythema nodosum, and pyoderma gangrenosum. Arthritis tends to involve large joints and be migratory and transient. One or more of these parallel disorders develops in > 1/3 of patients hospitalized with IBD.
2. Disorders that are clearly associated with IBD but appear independently of IBD activity. These include ankylosing spondylitis, sacroiliitis, uveitis, and primary sclerosing cholangitis. Ankylosing spondylitis occurs more commonly in IBD patients with the HLA-B27 antigen. Most patients with spinal or sacroiliac involvement have evidence of uveitis and vice versa. Primary sclerosing cholangitis, which is a risk factor for cancer of the biliary tract, is strongly associated with UC or Crohn's colitis. Cholangitis may appear before or concurrently with the bowel disease or even 20 yr after colectomy. Liver disease (eg, fatty liver, autoimmune hepatitis, pericholangitis, cirrhosis) occurs in 3 to 5% of patients, although minor abnormalities in liver function tests are more common. Some of these conditions (eg, primary sclerosing cholangitis) may precede IBD by many years and, when diagnosed, should prompt an evaluation for IBD.
3. Disorders that are consequences of disrupted bowel physiology. These occur mainly in severe Crohn's disease of the small bowel. Malabsorption may result from extensive ileal resection and produce deficiencies, of fat-soluble vitamins, vitamin B12, or minerals, resulting in anemia, hypocalcemia, hypomagnesemia, clotting disorders, and bone demineralization. In children, malabsorption retards growth and development. Other disorders include kidney stones from excessive dietary oxalate absorption, hydroureter and hydronephrosis from ureteral compression by the intestinal inflammatory process, gallstones from impaired ileal reabsorption of bile salts, and amyloidosis secondary to long-standing inflammatory and suppurative disease.
Thromboembolic disease may occur as a result of multiple factors in all three categories.
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| tompat
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yes the ans is c
what i meant is the explanation to rule out primary biliary cirrhosis, it beening primary cant be related to uc but primary sclerosing cholangitis do.
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| new_n_lost
Politically InCorrect
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Good Job PO 
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FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."
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| po
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thanks for positive reinforcement nnl,[ reading behav sci].
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| drduck
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C
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| Ig F
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c.......PBC...all other are associated with IBD......
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