Hotobhaga
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1) A 1400-g infant, born at 35 weeks' gestation, is 42 cm in length and a has a head circumference of 28 cm. One day after birth, she becomes very irritable, tremulous, and inconsolable. Her cry is high-pitched. Her pulse is 174/min. There are no dysmorphic facial features. To which of the following substances was this newborn most likely exposed in utero?
A. Alcohol
B. Barbiturates
C. Cocaine
D. Marijuana
E. Opiates
Explanation:
The correct answer is
C. The most commonly abused drug by pregnant mothers is cocaine. Infants are usually small for gestational age (SGA) and sometimes have microcephaly and neurodevelopmental abnormalities. Exposed infants are very irritable and inconsolable in the withdrawal period. Their cries are often high-pitched. They are also at increased risk of sudden infant death syndrome (SIDS). Periventricular leukomalacia (a CNS ischemic lesion) is also associated with cocaine exposure. Alcohol (choice A) abuse during pregnancy causes fetal alcohol syndrome. It is characterized by failure to thrive, cardiac defects, facial dysmorphic features (such as narrow forehead, microphthalmia, short palpebral fissures, and micrognathia), and neurologic abnormalities. Barbiturate (choice B) use during pregnancy causes the infant to have limb anomalies, mental retardation, nail hypoplasia, and some dysmorphic features, such as a short nose and a low nasal bridge. It is not usually associated with low birth weight and microcephaly. There is no clear evidence that marijuana (choice D) use during pregnancy is associated with any teratogenic effects on the infant in humans. In animal studies, however, it has been associated with fetal growth restriction and teratogenesis. Opiate (choice E) abuse during pregnancy is associated with a high incidence of obstetric complications, suach as placental abrqauption, preterm labor, and fetal growth restriction. Tremors, irritabilizty, vomiting, and diarrhea present in the neonatal period.
the answer should be oipiate withdrawl I suppose
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| elitoki
Forum Guru
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For Drug withdrawl in neonate:
first 24 hrs: cocaine
first week : opioid
>2 weeks: barbiturates~
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| dr in trouble
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first 48 hrs--heroine
1 wk--phenobarb
2--6 wks--methadone
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| cirus
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1st 48 hrs--> cocaine or heroin
1 wk ---> Phenobarb
>2 wks--> Methadone
but i found this :
Methadone is the only approved medication for treating opioid addiction during pregnancy
Pregnant women users who are in treatment with methadone deliver healthy babies. It is true that babies born to women on methadone sometimes experience some withdrawal symptoms during the first several days after birth. The symptoms are routinely treated by the baby's pediatrician and do not result in any long-term damage. In addition, babies born to women on methadone tend to have a slightly lower birth weight than babies of non-addicted control mothers. The most important comparison, however, is not how these babies compare with non-addicted controls, but rather how they compare with babies of mothers addicted to heroin. Studies that have compared babies born to mothers in methadone treatment with babies born to mothers who use heroin have demonstrated tremendous benefits from methadone.
Methadone treatment allows the mother to be followed in prenatal care, to receive nutritional supplements, information and to participate in parenting classes. The vast weight of evidence supports the use of methadone with heroin-addicted women to reduce the risk of miscarriage, increase birth weight, reduce infection and HIV risk to fetus, and generally produce a much greater chance for a healthy baby.
So anyone has any explanation for this
Edited by cirus on 07/12/07 - 01:55 AM
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