forumdoctor
Forum Senior
Topics: 14
Posts: 123
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Can any 1 explain, why in alpha thalassemia, HCT is decreased, when RBC is increased. ( HCT must also increse rt if RBC is increased)
I hope some one will explain.
gl
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| new_n_lost
Politically InCorrect
Topics: 652
Posts: 6,066
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Goljan RR 2nd Ed. Pg 197
Section II B point
2 Changes in Thalassemia
i) Hb and Hct r decreased
ii) RBC count is increased ( Unknown Mechanism)
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| po
Forum Elite
Topics: 39
Posts: 356
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There is uniform microcytosis in thalassemia,RDW helps here diff from iron deficiency anaemia where RDW IS INCREASED.That means microcytosis is not uniform.That what I remember.
So probably though the no is raised hct is less since volume is reduced.And Hct is total volume percentage of RBC'S ,or something like that.cant go beyond that.
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| SmokyWaters
Forum Elite
Topics: 6
Posts: 458
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I agree with new n lost...
may be microcytosis is so much that Hct is decreased while the number is increased....but unknown mechanism is whats the latest consensus
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