paganini
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A person is given a drug that dilates both the afferent and efferent arterioles. Assuming no other action of the drug, what will happen to the percentage of filtered sodium that this person's proximal tubule reabsorbs?
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| new_n_lost
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Dilation of Both Efferent and Afferent Leads to Dec GFR Which lead to Dec Filtered Load of Na.
Now the Proximal Tubular Reabsorption of Na is based on ATPases and ATPases do work against the Concerntration Gradient.
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| paganini
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It will decrease. This question focuses on the effect of peritubular factors on proximal sodium reabsorption. The GFR will remain about the same, but the filtration fraction will decrease (total renal vascular resistance decreases, so renal blood flow increases). The peritubular capillary pressure will, therefore, rise. At the same time, the peritubular oncotic pressure will decrease because of the decreased filtration fraction. Both of these effects tend to reduce fluid reabsorption from the interstitium, which reduces proximal sodium and water reabsorption.
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| paganini
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Good question no?
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| new_n_lost
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| drduck
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this wasnt so difficult......
dilating both increases the glomer flow
but decreases the filteration....
less time for tubular cell to catch the sodium.......
resorptin of sodium decreases
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