Renal drug x777

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Renal drug x777

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4 Posts

paganini
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Topics: 26
Posts: 159

06/29/07 - 09:34 AM

A drug is given that blocks all sodium channels and transporters in the luminal membrane all along the tubule but does not act on the Na-K-ATPase pumps in the basolateral membrane. What happens to sodium reabsorption?

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new_n_lost
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06/29/07 - 05:31 PM

Decreased ??

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paganini
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Topics: 26
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06/29/07 - 06:20 PM

Correct. It ceases completely. Even though the active step is not altered by the drug, there will be no sodium entering the cell to be acted on by the pumps.

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drduck
Forum Guru

Topics: 82
Posts: 529

07/02/07 - 12:37 PM

surely decrease.......
hey it will also have an effect on acid base buffer???
or not......

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