keepgoing
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newborn reflexes
Babinski: disappears by 2 years(((m i right medoc?)))
Rooting: disappears at 3-4 months
Sucking: disappears at 10 to 12 months
Palmar grasp: disappears at 3 to 4 months
Plantar grasp: disappears at 8 to 10 months
Tonic neck: disappears by 4 to 6 months
Moro (startle): disappears by 3 months
Stepping reflex: disappears by 2 months
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| mytime
Kick my butt!
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VERY GOOD, buddy! 
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| anuba
Forum Elite
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Keep going KG.. you are doing good!
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| medocuk
IM-RES
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Biochemistry in Neonates:
pH: 7.11-736
PO2: 8-24 mmHG
PCO2: 27-40 mmHG
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| medocuk
IM-RES
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Neurotransmitters:
Ach: all motor axons, autonomic preganglionic neurons,postganglionic parasympathetic fibres, some cells of motor cortex and basal ganglion.
Biogenic amines:
NE: postganglionic parsympathetic neurons
E: chromaffin cells of the adrenal medula
Serotonin: Brain stem cells
Histamine: Hypothalamus
Amino Acids:
Glycine: Inhibitory @ spinal interneurons
GABA: I, CNS
Glutamate, aspartate: Excitatory, CNS generates ESPS
Nitric Oxide:
Inhibitory in CNS and enteric nervous system.
Also functions as cellular signal transduction molecules.
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| medocuk
IM-RES
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Right you are, and thanks for this list.
keepgoing wrote: newborn reflexes Babinski: disappears by 2 years(((m i right medoc?))) Rooting: disappears at 3-4 months Sucking: disappears at 10 to 12 months Palmar grasp: disappears at 3 to 4 months Plantar grasp: disappears at 8 to 10 months Tonic neck: disappears by 4 to 6 months Moro (startle): disappears by 3 months Stepping reflex: disappears by 2 months
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| keepgoing
Forum Guru
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U are welcome medoc cool post!!
GH doesnt work directly on bones/gwoth of body, can anyone tell thn how it works???
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| mytime
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IGF-1. Liver.
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| keepgoing
Forum Guru
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mytime wrote:
IGF-1. Liver.
Edited by keepgoing on 07/17/07 - 06:54 AM
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| mytime
Kick my butt!
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TYPE COLLAGEN TYPE STR. TISSUE
I almost all Skin, bone, blood vessels.
Tendon, cornea
II Gel Cartilage, IV disc, vitreous body
III friable/ soft Blood vessels, fetal skin
IV Basement membrane
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| medocuk
IM-RES
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Measurement of Body Compartments:
ECF: Inulin, Na22
Plasma Volume: I125 albumin
ICF: Plasma volume -ECF
Total Body water: Heavy H2O
Blood Volume: Cr 15
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| keepgoing
Forum Guru
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medoc i juz(rt now) did this question from qbank physio was going to post  thanks..
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| keepgoing
Forum Guru
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medocuk wrote:
Measurement of Body Compartments:
ECF: Inulin, Na22
Plasma Volume: I125 albumin
ICF: Plasma volume -ECF
Total Body water: Heavy H2O
Blood Volume: Cr 15
juz correction in ICF place should be ISF..CALCULATE interstitial fluid compartment with plasma vol - ECF
and ICF= TBW-ECF
thanks medoc!!
Edited by keepgoing on 07/18/07 - 07:14 AM
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| mytime
Kick my butt!
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MOLECULAR CHAPERONES
functionally active, newly synthesized protein chains must fold in to unique three-dimensional structures. Although the native fold of a protein is encoded in its amino-acid sequence, protein folding inside cells is not generally a spontaneous process. Many newly synthesized proteins require a complex cellular machinery of molecular chaperones and the input of metabolic energy to reach their native states efficiently. The various chaperone factors protect non-native protein chains from misfolding and aggregation, but apparently do not contribute conformational information to the folding process. Many chaperones are also stress- or heat-shock proteins (HSPs) that prevent unstable proteins from aggregating under various conditions of conformational stress. Other important functions of chaperones include the stabilization of preproteins for membrane translocation, the presentation of misfolded proteins to the proteolytic machinery and the conformational regulation of signalling molecules. The underlying principle in all these functions is the recognition by chaperones of proteins in their non-native states.
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| mytime
Kick my butt!
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Please put "To become " in the front of the para . It's not getting edited. 
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| mytime
Kick my butt!
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Ubiquitin-Proteasomal degradation
a. Half-life determined by protein sequence (N-end rule) b. Proteasomal degradation occurs in cytosol and nucleus c. Ubiquitin signal i. added to proteins as a degradation signal - added to <?xml:namespace prefix = st1 ns = "urn:schemas-microsoft-com:office:smarttags" />Lys - Ubiquitin is polymerized ii. attached by 3 different ubiquitinating enzymes iii. Protein must be polyubiquitinated (at least 3 Ubqs.) d. Proteasome i. large (26S) multi-subunit complex ii. binds ubiquitinated proteins
[font=" Times New Roman??>e. Proteasome unfolds and degrades the protein completely
Lysosomal degradation a. Lysosomes contain many proteases and other acid hydrolases i. Cathepsins [/font]- lysosomal proteases - optimal activity at pH 5 - chloroquine (anti-malarial drug) increases lysosomalpH b. Lysosomes fuse with vesicles containing molecules to bedegraded i. from internalization of externalmolecules[col or=#000000] ii. autophagic vacuoles - [/color]from intracellular molecules c. Disease states may increase or decrease lysosomal degradation i. diabetes mellitus increases lysosomal breakdown ii. regression of the uterus after childbirth increaseslysosomal breakdown iii. rheumatoid arthritis increases extracellular release oflysosomal enzymes iv. lysosomal storage diseases are genetic absences ofspecific acid hydrolases
How is the smooth endoplasmic reticulum able to detoxify drugs and poisons?
The smooth endoplasmic reticulum is richly concentrated in enzymes that specialize in making chemical modifications to drugs, particularly in liver cells. Mixed function oxidases are important in this role because they specialize in oxidizing, in most cases literally adding oxygen atoms to drug molecules. This process makes sense, since drugs most commonly stay in the body; they are not very soluble in water and therefore are not passed through the urine. Even when drugs travel through the bloodstream, they remain bound to plasma proteins and other things in the blood and thus remain invisible to the kidney.
<?xml:namespace prefix = v ns = "urn:schemas-microsoft-com:vml" />s
The enzymes in the smooth endoplasmic reticulum of the liver try to make drugs more soluble in water. One way to do this is to make them more "polar," in other words, to add electronegative atoms such as oxygen to the structure. In many cases, the same modifications that make a drug more water soluble also eliminate its intended effect. Therefore, they are being handled by liver enzymes, the drug molecules no longer work.
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| keepgoing
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thanks MT.
ADH acts both at late distal and collecting kidney tubules,but maximum water absorption will be at proximal tuble only(65-67%) irrespective of increase or decrease ADH levels or any other cause...(((((saw two question on kaplan based on this understanding only))
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| mytime
Kick my butt!
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a. Adenovirus therapy for cystic fibrosis
b. Insertion of vascular endothelial growth factor (VEGF) genew into heart muscle to induce blood vessel formation
c. retrovirus therapy for adenosine deaminase ADA) deficiency
d. Lung cancer treatment by insertion of normal p53 genes into tumor cells
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| keepgoing
Forum Guru
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ok folks!!
letsimagine a woman workouting at gym..sitting on excersise machine---acc.to her postions and action what nerve would be responsible for that particular action??
1.if resistence is from lateral sides of her thighs and she is pressing against it--->
2.if resistence is from medial and she is to press against it--->
3.she is lefting weigth up with her feet ----->
4.same she is pulling it down---->
5.now she stand and stand on her toes---->
who can answer..all have done one read..so try all(good revision of lower limb nerves)
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| mytime
Kick my butt!
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2. Abductors of thigh. I'm still scratching!!!! 
1. Obturator n. supplying the adductor gp.
3. extensors of thigh/ knee joint ----- Rectus femoris: Femoral n.If u mean just the foot movement then dorsiflexors, Deep peroneal n.
4. Now again if u mean the plantar flexors the Tibial n. coz plantar flexion.
5. extensors (hamstrings.and extensor gp of muscles.) Gluteal n. and femoral and so many more I wish i knew what u were trying to ask specifically. 
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| keepgoing
Forum Guru
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good try mytime..lets see
1..hip abduction-->sup.gluteal nerve
2.hip adduction--->obturator n
3.extensor of knee-->femoral n.
4.knee flexor-->sciatic n.
5.tibial n
good way to remember with gym activity..isnt it!!
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| mytime
Kick my butt!
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They'll probably wil ask just like this!
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| keepgoing
Forum Guru
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An easy way to learn ODC--
The loading of O2 is facilitated when the oxygen dissociation curve shifts to the left, and the unloading of O2 is facilitated when the oxygen dissociation curve shifts to the right. A good way to remember the conditions that promote dissociation of O2 is to think of exercising muscle, which has decreased pH because of the accumulation of lactic acid, increased PCO2 because of the increased rate of aerobic metabolism, increased temperature and increased 2,3-DPG (2,3-diphosphoglycerate)because of increased glycolysis.
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| keepgoing
Forum Guru
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PSYCHOLOGICAL ASSESSMENT TESTS---
The Halstead-Reitan Battery is a group of tests that reflects the basic and higher level cognitive and neuro-sensory functioning of the entire brain, and can be used in a serial fashion with little learning effect being present. .
The Stanford Binet Intelligence Test --used in the adult, mainly reflects verbal skills
. The Vineland Adaptive Behavior Scale assesses developmental and social functioning, not cognitive and neuro-sensory abilities.
The Wechsler Adult Intelligence Scale confines its results to intelligence assessment and does not assess more basic issues like aphasia and neuro-sensory skills.
The Wide Range Achievement Test assesses academic achievement only.
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| paheli
It'sAllAboutGoodKarma
Topics: 177
Posts: 2,368
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hey, how come i missed this golden thread?? will be back with stuff, guys! thanks!
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Prepare as if you're the worst, Perform as if you're the best! As you dream, so you manifest. So, DREAM BIG!! When you face hardship, remember, God never gives you more than you can handle. Keep your face to the sunshine and you cannot see the shadows.
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