Prep4USMLE Forum » USMLE Step 2 CK Forum » Internal Medicine Forum |   calcium in alkalosis

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doc08 Forum Senior Topics: 9 Posts: 153	06/27/07 - 09:48 PM             #1 can anyone please describe why ionized calcium become low in metabolic alkalosis? it is becuase of trancellular shift to compensate H+ movement???
Hotobhaga Forum Elite Topics: 41 Posts: 180	06/27/07 - 09:59 PM             #2 The albumin get more negatively charged in alkalosis. That binds more ionised calcium causuing a decrease in the ionosed fraction. This causes oversensitization or peripheral nerves and nM junctions causuing carpopedal spasm. Most commonly seen in hyperventilating women in stress. ___________________ USMLE preparation is all about discovery. Discovery of your own capabilities....Julia Perch MD (iprep)
doc08 Forum Senior Topics: 9 Posts: 153	06/28/07 - 03:41 PM             #3 thanks buddy your answer made me recall concept from step 1 endocrine ratio of free to bound ca2+ is pH dependent, it decreases in alkalosis and increases in acidosis !!!!!!

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Similar forum topics Metabolic Alkalosis Metabolic ALkalosis Contraction Alkalosis Metabolic Alkalosis

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