new_n_lost
Forum Hero
Topics: 724
Posts: 6,386
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UW says that Antimetabolites Act on G1 phase and S phase While Katzung Board Review says that Antimetabolites r Cell Cycle Specific and they act only on the S phase of the Cycle.
Any Thoughts on this Point. 
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| drduck
Forum Guru
Topics: 82
Posts: 523
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i follow lippin........clearly mentions.......cell cycle specific....S phase..
the name itself suggests.......has actions on of purine and pyimidine metabolites.....all has to happen in S phase.....not G1
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| drhouse
Forum Elite
Topics: 25
Posts: 225
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i agree with drduck.
antimetabolite affect only S phase. coz action of them is to inhibit pyrimidine and purine synthesis which occur only in S phase
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