cirus
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Everyone knows that the most comman cause for Euvolemic Hyponatremia is SIADAH...
In the endocrine sec of Kapl notes, the clearly states that it causes mentained hypervolemia?? & the interesting part is that I've gone over it a dozen of times but I didn realize it..So i thought someone else would have memorized it wrong, so take care guys & GL
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| DrVirgo
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Good point. SIADH, so increase in ADH which puts water channels in the Collecting duct of the nephron, and more H2O goes from tubule to blood, thus diluting effect and hyponatremia.
Can you please explain the mechanism WHY the patient is also EUvolemic and not HYPERvolemic?
Thanks.
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| ssrpk
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because one important determinant of total body water is total body sodium...which will not be increased in SIADH
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| ssrpk
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besides this mistake is recrtified in kaplan ... check out new editions
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| tolito
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i am thinking that you mean to say there is no edema despite the increase in volume. the volume of water increases due to kidney preservation of free water but there is no edema because there is associated natriuresis. so total body sodium is low. i think kaplan is right.
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| doyoudig
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yes there is a Na Escape mechanism at work here, which leads to Euvolemia rather than hyervol
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