Jackofknives
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Man this is pushing the details
I've never heard of a reticular formation in the tegmentum of the midbrain since the tegmentum there is fairly thin in structure, however there is a upper pontile reticular which secretes ACh, acts as general arousal of the mind together with locus cerulus (spelling?) which secretes NE. Lesion here will result in Coma.
That would be C.
You will have some kind of REM signal under whatever condition, so that s not a good distinctive answer. I dunno the etiology for narcolepsy but it doesn’t seem to the answer.
By intractable pain you are probably referring to neurogenic hyperalgesia, such as phantom pain as a result of amputation, which cannot be managed by pain killers. We think this is due to, for 1, aberrant regeneration of the peripheral nerves and theirs ion channels causing spontaneous activation, and a plastic rearrangement of the pain area in the parietal lobe.
Edited by Jackofknives on 06/23/07 - 12:16 PM
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| me007
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reticular formation - regulation of muscle and reflex activity, control of respiration, cardiovasc. responces, behavioraal arosal and sleep.
in acute lesion could be insomnia.
not sure though
periaqueductal gray - opiod receptors, pain modulation.
if acute destruction - pain can be a choice
Edited by me007 on 06/23/07 - 09:56 PM
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| Jackofknives
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First I want to correct something i wrote above. I was thinking EEG when referring to REM. Ofc REM is short for rapid eye movement during sleep, in which state, your EEG is showing beta wave, this is peculiar because during REM your brain is in a very aroused condition, as active as when you are solving complex math problems.
During REM our upper pontile reticular formation is very active. During deep sleep, i.e. EEG of theta and delta waves, raphe nuclei in the medulla oblongata (which secretes serotonin) is very active.
Now sleep and wakefulness, according to contemporary theory, is a constant battle between the nuclei that arouse (upper pontile reticular, locus cerulus etc) and those that inhibit (raphe nuclei, sleep factors etc).
As a rule of thumb, lesion above the CN5 nuclei results in coma whereas lesion below results in permanent awakefulness, i.e. insomnia and you will probably die due to fatigue.
I think you can read about it in Guyton P740-741, not sure though.
me007 • those homeostasis regulatory functions belong to reticular formation in the oblongata as far as I know.
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| me007
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what about periaqueductal? is it there were tegmentum is?
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| Jackofknives
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Blah I have to correct something again. Tectum in the midbrain is thin, tegmentum on the other hand is not thin.
Here is a picture of the reticular formation hierarchy http://en.wikipedia.org/wiki/Image:Reticulah.jpg
periaqueductal grey is not involved, but yea its in the tegmentum.
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| kingusmle
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it is loss of consciuosness
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| aml
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C- loss of consciousness-ARAS
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| ieltsforall
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C LOSS OF CONSCIOUSNESS
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