A 40-year-old female

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A 40-year-old female

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7 Posts

drduck
Forum Guru

Topics: 82
Posts: 529

06/18/07 - 08:56 AM

A 40-year-old female with a history of AIDS develops a herpes simplex
keratitis of the eye. Which of the following antiviral agents should be administered in this case?

a. Zanamivir

b. Trifluridine

c. Zidovudine

d. Amantadine

e. Indinavir

valodik
Forum Newbie

Topics: 5
Posts: 30

06/18/07 - 09:55 AM

po
Forum Elite

Topics: 39
Posts: 356

06/18/07 - 11:23 AM

these q r difficult and depressing;

po
Forum Elite

Topics: 39
Posts: 356

06/18/07 - 11:41 AM

need some more such q,esp on HIV;
lot of questions detailed review of the whole topic,some confusing.

http://depts.washington.edu/hivaids/index.html

dncosta
Licensed, finally
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Topics: 19
Posts: 604

06/18/07 - 11:43 AM

B; Idoxyuridine or Acyclovir would also be correct

new_n_lost
Politically InCorrect
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Topics: 654
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06/18/07 - 07:46 PM

dncosta wrote:
B; Idoxyuridine or Acyclovir would also be correct

b. Trifluridine
nod

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drduck
Forum Guru

Topics: 82
Posts: 529

06/19/07 - 06:08 AM

ya...even i cudnt get thru....first time....
antiviral reading was superficial...

answer is B.....

Trifluridine inhibits viral activity in HSV types 1 and 2, CMV, vaccinia, and perhaps adenovirus. It acts as a viral DNA synthesis inhibitor by irreversibly blocking thymidylate synthetase.
Trifluridine triphosphate is a competitive inhibitor of thymidine
triphosphate accumulation into DNA. It is used in the treatment of primary keratoconjunctivitis and recurrent epithelial keratitis caused by HSV 1 and 2.

good job those who got it right smiling face

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