asmi
Forum Hero
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why does a baby with this anemia doesnot show symptoms at birth ?
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| peekay
Forum Guru
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because of persistent hgbF persist for some time. as a fact SC dz is not diagnoses until after 6 months
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| asmi
Forum Hero
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correct 
there is increased HbF and thus decreased HbS at birth and few months after it ( may be 6 months to 1 yr)
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| Ig F
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and fetal hemoglobin is less prone to hypoxia because it doesnt bind to 2,3-BPG strongly...
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| 1.ammara
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and also HbF interferes and inhibits the polymerization of HbS under deoxygenated state.
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