drduck
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A 5 yr old child who presents with H/O recurrent infections with gram posistive bacteria such as staph aureus is found to have genetic lack of beta-2 integrins. Which of the following abnormilities of neutrophil function is responsible for his clinical symptoms?
A-neurophils show normal rolling but inadequate sticking on cytokine activated endothelial cells
B-failure of neutrophils to migrate to the site of infection after leaving the vasculature
C-reduced respiratory burst in neutrophils after phagocytosis of bacteria
D-diminished phagocyosis of the bacteria opsonised with immunoglobulin G
E-failure to generate hydroxy-halide radicals(HOCl)
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| Medusin
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A.
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| peraspera
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A. Leukocyte adhesion deficiency ( absence of cd 18- b chain integrins )
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| doc179
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A
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| new_n_lost
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A-neurophils show normal rolling but inadequate sticking on cytokine activated endothelial cells
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| SILVER
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A
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| drduck
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ok fine u all done well with patho..........
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| Addicudo
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A-neurophils show normal rolling but inadequate sticking on cytokine activated endothelial cells
CD-18 I guess ... ??
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| Addicudo
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As peraspera said ..
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