DrVirgo
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A 45 year old woman consults the physician because chronic fatigue. A review of systems reveals lont standing stomach problems characterized by slow digestion and delayed emptying of her stomach. A complete blood count bemonstrates a moderately severe megaloblastic anemia.
Serum Vitamin B12 level is 85pg/mL;
Serum Folate is 3 ng/mL; and
serum Iron is 105 mg/dL.
Autoantibodies to Intrinsic factor are detected in the serum. A biopsy of the stomach is most likely to show with of the following?
A. Acute erosive gastritis
B. Gastric atrophy
C. Linitis plastica
D. Menetrier disease
E. Peptic ulcer
WHY?
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| doc_clotaire
Forum Guru
Topics: 159
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B. Gastric atrophy
Autoantibodies to Intrinsic factor ------Pernicious anemia -----gastric atrophy
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| prathapdoctor
Forum Elite
Topics: 12
Posts: 406
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pernicious anemia, type A gastritis leading to atrophy of body and fundus of stomach.
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| DrVirgo
Forum Hero
Topics: 1096
Posts: 3,515
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Yes, B.
Pernicious anemia, gastric atrophy assoc. w/megaloblastic anemia b/c B12 deficiency
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