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 weightloss pill? what are they  



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Author18 Posts
  #1

when there is a vingette of a person on weightloss pills, what drugs are we suppose to suspect? thanx




  #2

probably consider pills that contain thyroid hormones



  #3

nodnod


  #4

http://content.nejm.org/cgi/content/short/335/9/609


  #5

The distinctive valvular abnormality seen with fenfluramine is a thickening of the leaflet and chordae tendinae. Roth (2007) suggested a mechanism by which fenfluramine damaged the valves. Heart valves also have serotonin receptors, which regulate their growth. He reported that fenfluramine and its active metabolite norfenfluramine stimulated the serotonin receptors 5-hydroxytryptamine (5-HT). In particular norfenfluramine is a potent agonist (stimulant) of 5-HT2B receptors. These receptors are plentiful in human cardiac valves and appear to be essential for normal cardiac development.


  #6

ok so its thyroid hormones and seratonin modulators?


  #7

uw has q on this - after time pt had pulm hypertension


  #8

what about amphetamines????


  #9

pharmacologic agents for weight loss (not for thyroid disorder)
1. orlistat - pancreatic lipase inhibitor, limits breakdown of dietary fats
2. sibutramine - blocks monoamine reuptake, incr feeling of satiety.

fenfluramine - discontinued in US




  #10

thanks buddy


  #11

[quote=rishta]shuoudnt amphetamines be in the list too as it decreases appetie?[/quote]



  #12

http://www.medscape.com/viewarticle/562497_print


  #13


this link asks for log in info. can you post the article?


  #14

silver wrote:

this link asks for log in info. can you post the article?

Well i have Attached the Article for u in a Word format cos the article was too long to be posted here.


Attached Files:
Pharmacotherapeutic Options for Overweight Adolescents.doc (254 KB, 24 downloads)

  #15

orlistat?


  #16

Thanks nnl!


  #17

orlistat is the most commonly used weightloss pill...although fenfluramine and thyroid hormones can also provide desired effects with undesirable side effectz....


  #18

me007 wrote:
pharmacologic agents for weight loss (not for thyroid disorder)
1. orlistat - pancreatic lipase inhibitor, limits breakdown of dietary fats
2. sibutramine - blocks monoamine reuptake, incr feeling of satiety.

fenfluramine - discontinued in US




Fenfluramine causes pulmonary hypertension, I think thats why its discontinued. and is a weight loss pill






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