aspirin

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aspirin

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10 Posts

whournameiz
Forum Senior

Topics: 40
Posts: 94

06/07/07 - 02:32 PM

Aspirin inhibits

a) cox-1
b) cox-2
c) 5 lipoxygenase
d) 3 lipoxygenase.

po
Forum Elite

Topics: 39
Posts: 356

06/07/07 - 02:44 PM

is non selective,irreversible inh of both a&b. nod

drduck
Forum Guru

Topics: 82
Posts: 523

06/08/07 - 08:07 AM

what was that......
both a and b....
what is the source....did this Q come somewhere???

shocked

po
Forum Elite

Topics: 39
Posts: 356

06/08/07 - 09:16 AM

IE why they got new selective cox 2[rofecoxib,celecoxib] thinking they wont hav increase acidity as sideeffect, and if u hav heard news about all the these drugs getting a black box warning telling you long term they might get cardiotoxicity.

whournameiz
Forum Senior

Topics: 40
Posts: 94

06/08/07 - 01:30 PM

source is step1

keepgoing
Forum Fanatic
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Topics: 104
Posts: 2,230

06/08/07 - 10:44 PM

hey i think its cox 1,rememberd dr goljan saying asprin inhibits cox1 not cox 2..

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drduck
Forum Guru

Topics: 82
Posts: 523

06/09/07 - 01:23 AM

aspirin is NON SELECTIVE.....

i dont know if any new theory has come but before that aspirin was non selective.....

it relieves pain....and erosive action in GIT, inhibition of PGs....
antiplatelet action.....
all cannot be cox 1 or cox 2
it has to be both.....

jazpu.
Forum Newbie

Topics: 0
Posts: 3

06/15/07 - 10:22 AM

aspirin causes an irreversible inhibition of COX. Covalent bond via acetylation of a serien hydroxyl group near the active site. both COX 1 and COX 2.
source: USMLE Step 1 pharmacology lecture notes KAPLAN.

SILVER
DoWhatYouGotToDo!
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Topics: 22
Posts: 892

06/15/07 - 11:32 AM

aspirin irreversibly inhibits cyclooxygenase--therefore both COX-1 & COX-2 are inhibited

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new_n_lost
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Topics: 674
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06/15/07 - 02:07 PM

#10

silver wrote:
aspirin irreversibly inhibits cyclooxygenase--therefore both COX-1 & COX-2 are inhibited

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