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Kaplan Qbank USMLE



Author7 Posts
  #1

which of the following inhibits thrombin activity ?

A. factor XIIIa
B. fibrin monomers
C. a1- antitrypsin
D. dermatan
E. a2- antiplasmin

  #2

B.

  #3

it is C a1-Antitrypsin

  #4

sorry,
correct is 1-antitrypsin
Disorders of the enzyme include alpha 1-antitrypsin deficiency, a hereditary disorder in which lack of alpha 1-antitrypsin leads to uninhibited tissue breakdown during inflammation. This causes pulmonary emphysema and leads to liver cirrhosis in severe cases.
A remarkable form of Pi, termed PiPittsburgh, functions as an antithrombin (a related serpin), due to a mutation (Met358Arg). One patient with this abnormality has been described; he died of a lethal bleeding diathesis.


  #5

good Q....
shaking headshaking head

  #6

Guys, I have no idea what the answer to this q is. I got this q from an older thread on this website and it didn't have any explanations.

So unfortunately, I can't say what the right answer is.

  #7

shaking headshaking head







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