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Kaplan Qbank USMLE



Author3 Posts
  #1

A quick review of the qs not posting the whole qs as it is too long.

A pedigree of a family shows carcinoma breast,myxofibrosarcoma,medulloblastoma and rhabdomyosarcoma running in a family illustrates
a.incomplete penetrance
b.multifactorial inheritance
c.genetic heterogeneity
d.variable expressivity

what is it?
i am thinking of b..nothing else is coming in my head at this point...what do u guys say?

  #2

Some cancers cluster in families as the result of a combination of genetic and shared environmental factors (multifactorial influences). In such cases, generally speaking, the closer in relation a family member with cancer is to you (i.e. the more genes you share in common), the higher your chance to also develop cancer. In other words, it is more significant for your personal health if one of your parents or siblings develops cancer (or other disease), than if your second cousin develops the disease.
B. is correct

  #3

can it by any chance be genetic heterogeneity







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