Colombia
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How many ATP's are produced in anaerobic conditions?
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| asmi
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Total ATP produced depends on whether malate or glycerol phosphate shuttle is used.
* 8 ATP's if malate shuttle is used ,( 3 x 2 = 6 + 2= 8)
* 6 ATP's if glycerol shuttle is used ( 2x2= 4+ 2= 6)
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| asmi
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* eight ATP's from malate shuttle .
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| usmleasr
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do u mean in anaerobic conditions..? is it 8 ATPs... :roll:
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| asmi
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8 ot 6 depending upon shuttle's used ( malate/glycerol P04 )
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| Colombia
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No 
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| asmi
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no :cry: then what is the answer ( i read that from kaplan) ?
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| asmi
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overall reaction :
glucose+ 2Pi + 2ADP---> 2 lactate + 2 ATP + 2 H2O.
* 2 molecules of ATP are generated for each mol. of glucose converted to lactate .
* but what about ATP's from the shuttles ?
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| Colombia
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In anaerobic conditions 2 ATP are producted +lactic acid.. Although NADH's are produced, they can not be used in the mitochondria (oxygen is required).
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| usmleasr
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yes i agree
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| asmi
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can anybody clear this to me...what about the ATP's generated from the shuttles ???
kaplan clearly mentions that total ATP's produced by anerobic glycolysis depends on using malate /glycerol shuttle .
Should we write 2 ATP's (as given above ) or ??
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| Colombia
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No oxygen=no oxidative phosphorilation=NO ATP's are produced from NADH and FADH. The only ATP available come from direct formation.In this case just two.
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| asmi
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yes i agree with that but i wonder why kaplan will give wrong info .. :roll:
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| usmle prep
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FIRST AID 2004 on page 151.........
aerobic metabolism of glucose produces 38 ATP via MALATE SHUTTLE,
& 36 ATP via G3P SHUTTLE.
anaerobic glycolysis produces only 2 ATP per glucose molecule.
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| Waziri
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The 2NADH+ produced are reutilized in the reductin of 2pyruvates to 2lactates which are the end products of anaerobic glycolysis.
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| asmi
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thanks
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