ANTIBODIES ONLY SEEN IN LUPUS PATIENTS

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ANTIBODIES ONLY SEEN IN LUPUS PATIENTS

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6 Posts

asmaali_h
Forum Newbie

Topics: 4
Posts: 11

06/05/07 - 01:52 PM

WHICH ARE THE TWO ANTIBODIES ONLY FOUND IN LUPUS PATIENTS

cirus
Forum Guru
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Topics: 108
Posts: 740

06/05/07 - 02:01 PM

anti-ds-DNA abs( indicating kidney affection esp when rising---->Poor indcator)
anti-SM abs (lupus only)
Anti-Histone abs---->Drug induced Lupus
Anti Phospholipid abs---only significant in preg fem--->high risk of misscarriage(LMWH through preg)+/- Thromboembolic risk but not as in preg nod

DrVirgo
Forum Hero
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Topics: 1096
Posts: 3,515

06/05/07 - 03:41 PM

anti-ds DNA
anti-SM

Both of these are SPECIFIC antibodies to LUPUS ONLY.

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yash2
Forum Newbie

Topics: 2
Posts: 8

06/05/07 - 03:52 PM

Anti-SM
and
Anti-DsDNA :
Systemic Lupus Erythematosus (60%)
Associated with Lupus Nephritis
Associated with Lupus CNS Involvement
also seen in- not so frequently though -but no harm in knowing these
Sjogren's Syndrome
Rheumatoid Arthritis
Chronic active hepatitis
Biliary Cirrhosis
Epstein Barr Virus
Cytomegalovirus

cheers !

asmaali_h
Forum Newbie

Topics: 4
Posts: 11

06/06/07 - 10:26 AM

thanks guys.

arlete
Intern in 2009!!!!!

Topics: 41
Posts: 2,915

06/06/07 - 11:06 AM

anti-Sm is highly specific but not very sensitive for LES (only 30-40%), according to usmleworld.

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