epica
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per UW, antimetabolites belong to G1 while alkylating agents are s phase
but in other books, antimetabolistes are s phase drug, alkylating agents are cell cycle non-specific .
which is correct? thanks
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| drduck
Forum Guru
Topics: 82
Posts: 523
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lippin......says,
Antimetabolites.......S phase.....
alkyalting agents...........G1.......and sometimes S phase.......
was there any Q........which u got wrong bcos of this difference in opinions????
i not nothing to worry as every second author has new opinion.......but most of the books agree with what is written above.
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| new_n_lost
Forum Hero
Topics: 732
Posts: 6,453
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Alkylating agents r CCNS (Cell Cyclic Non Specific) they kill the tumor cells in both their cycling and resting of the cell cycle.
Antimetabolites CCS (Cell Cylic Specific) they attack the cells during the S phase cell cycle.
Reference Katzung.
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| epica
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Thank you, guys
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