whournameiz
Forum Senior
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1st aid says that Zollinger-Ellison and excess vit A cause hypercalcemia...does anyone know how???
thanx
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| silver
Forum Guru
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Posts: 771
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Z-E is part of MEN-I which is tumors of pit. gland, parathryoid, and pancreas assoc. with peptic ulcers and Z-E synd.
have no clue about excessie Vit. A causing hypercalcemia
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| new_n_lost
Politically InCorrect
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Vitamin A in high doses, such as those found in retinoid therapy for acne, can directly stimulate bone resorption by functioning as a transcription factor in osteoclast stimulation. Trans-retinoic acid, used for treatment of some leukemias, can elevate calcium with this mechanism, particularly when coupled with voriconazole.
had to search for it
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| silver
Forum Guru
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interesting 
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| ssrpk
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| whournameiz
Forum Senior
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thanx!!!!!
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| Tiff
Forum Guru
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How does hypercalcemia cause diabetes insipidus?
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