fox
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49. A 62-year-old man with metastatic prostate cancer
has a rising PSA level despite treatment with
leuprolide and flutamide. What should be the first
step in managing this asymptomatic man with hormone-
refractory disease?
A) Treat with aminoglutethimide
B) Discontinue flutamide to attempt to obtain an
antiandrogen withdrawal response
C) Discontinue leuprolide
D) Treat with diethylstilbestrol
E) Perform an orchiectomy
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| hanialkhadher
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D!
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| sridevibandaru24
Forum Guru
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E?
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| young_doc
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At first i'd say DES:
"In the 1990s, the only approved indications for DES were treatment of advanced prostate cancer and treatment of advanced breast cancer in postmenopausal women."
BUT, "The last remaining U.S. manufacturer of DES, Eli Lilly, stopped making and marketing DES in 1997." !?!?!
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| sailing boat
Forum Elite
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so whats the answer
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| doyoudig
Forum Guru
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if its refrcatory would u go for orchiectmy next?
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| fox
Forum Guru
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Posts: 727
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got u guys on the wrong foot!! Read this & u'l know the answer.
http://www.prostate-cancer.org/education/andeprv/...
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| Akeen
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Answer is B then.
Interesting stuff.
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| fox
Forum Guru
Topics: 70
Posts: 727
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Its B allright...hope we dont get such qs in real xam
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