|   nbme 2 Q, please explain your answer 
 
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| Author | 7 Posts |
nadiabarati
| | 05/29/07 - 11:33 AM  
 
   
 
|   #1 |
Dec 28, 06 - 08:37 [+] [-] #1 A 47-year-old woman who is visiting from Australia comes to the physician because of increasing urine output over the past month. She has had no dysuria or hematuria. She has a history of chronic headaches, peptic ulcer disease, and urinary tract infections. An evaluation 18 months ago for headaches, including CT scan of the head, showed no abnormalities; treatment with ibuprofen and phenacetin was initiated at that time, and her headaches have been well controlled. Her temperature is 37.1 C (98.8 F), blood pressure is 140/82 mm Hg, pulse is 78/min, and respirations are 14/min. Examination shows no abnormalities. Laboratory studies show: Hematocrit 32% Mean corpuscular volume 88 µm3 Serum Glucose 130 mg/dL Creatinine 1.7 mg/dL Urine Protein 2+ WBC 8–10/hpf RBC none Bacteria none Nitrates none Test of the stool for occult blood is negative. Which of the following is the most appropriate next step in management? A ) Intravenous pyelography B ) Discontinue current medication C ) Antibiotic therapy for recurrent urinary tract infections D ) Insulin therapy for diabetes mellitus E ) Upper endoscopy
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| gilbert Forum Junior
Topics: 16 Posts: 45
| | 05/29/07 - 12:11 PM  
 
   
 
|   #2 |
B, interstitial nephritis?
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| smal Forum Guru

Topics: 140 Posts: 727
| | 05/29/07 - 10:15 PM  
 
   
 
|   #3 |
B seems to be the only likely possiblity
___________________ remedy for weakness is not brooding over it ,but thinking of strength.
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| prasannakumar Forum Senior
Topics: 24 Posts: 55
| | 05/29/07 - 11:32 PM  
 
   
 
|   #4 |
A.. In analgesic nephropathy IVP reveals a ring defect
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| Akeen Forum Newbie

Topics: 1 Posts: 37
| | 05/30/07 - 04:27 AM  
 
   
 
|   #5 |
C. Discontinue. First step medication induced interstitial nephritis is suspected is o stop the medication.
___________________ I never give up or lose faith.
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| Akeen Forum Newbie

Topics: 1 Posts: 37
| | 05/30/07 - 04:28 AM  
 
   
 
|   #6 |
Anything about "Australia" in this question?
___________________ I never give up or lose faith.
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| prathapdoctor Forum Elite
Topics: 12 Posts: 406
| | 05/30/07 - 05:17 AM  
 
   
 
|   #7 |
I think its analgesic induced nephropathy, first step must be discontiinuation of analgesic then the diagnosis has to be confirmed by IVP.
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