asmi
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what is the development ( embryology) ?
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| doc4mindia
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The first indication of the formation of the prostate is an increase is cellularity of the splanchnic mesoderm surounding the proximal part of the urethra.
During week 10 :arrow: the androgen responsive urogenital sinus mesenchyme induces epithelial buds in the presumptive prostatic urethra. Initially, 14 to 20 solid epithelial buds in at least 5 groups grow into the surrounding mesoderm, this is the presumptive peripheral glandular area. Shortly afterwards a second phase of budding gives rise to the internal glandular area. The solid buds extend and branch under mesodermal control.
By the 11th week :arrow: lumens form within the epithelial cords and cellular end buds form primitive acini. Mesenchymal cells differentiate into smooth muscle, fibroblasts and blood vesels.
During the 12th week :arrow: the epithelium continues to proliferate while connective tissue septae extend into the acini, the stroma of the gland thins as the ducts and acini expand.
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| asmi
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thanks :idea:
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