goodies
Forum Junior
Topics: 19
Posts: 39
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44) A 50 yo man who has had a MI was diagnosed as having familial hypercholestermia, an AD disorder. HIs son has not been tested. Whats the probability that the patient's granddaughter, through his son, will have hypercholestermia?
a) less than 1%
b) 10%
c) 25%
d) 33%
e) 50%?
whats the answer and how do you figure it out? i dont get it
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| kingusmle
Forum Elite
Topics: 32
Posts: 270
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e is the answer ,coz AD alleles relatively rare so recurrence risk can either be 50% or 75% ...50% if AA X aa and 75% if Aa x Aa...assuming that the son has no dz at all then the answer shud be no disease transmitted to granddaughter ..not a choice!
tell me if i am wrong
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| lq2006
Forum Elite
Topics: 43
Posts: 382
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25%
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| kingusmle
Forum Elite
Topics: 32
Posts: 270
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what syour explanation lq2006?
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| sss sss
Forum Senior
Topics: 8
Posts: 203
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the probability that the son will inherit it is 50& or 1/2, the probability that the grand daughter will inherit it from the father is another 50% or 1/2, you have to multiple the 2 since they are 2 independent events, that gives you 25%.
so i also go with 25%
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| Addicudo
Forum Guru
Topics: 124
Posts: 608
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25% .. as sss sss said .. !
___________________
... Idle hands are the DeVilS play ground ...
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| kingusmle
Forum Elite
Topics: 32
Posts: 270
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thanks guys ..i guess i went onto the wrong side
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| goodies
Forum Junior
Topics: 19
Posts: 39
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how do you know the son doesn't have it and that its not being transmitted 100%??? =(
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| nimer1456
Forum Newbie
Topics: 1
Posts: 19
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I agree with 25%
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