Addicudo
Forum Guru
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In acute anteroseptal MI.the normal myocardium shows:
a) decreased bcl2 expression.
b) Increased P53 expression
c) Increased Bad expression.
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| keepgoing
Forum Guru
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 but b perhaps
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| drduck
Forum Guru
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in MI there is necrosis not apoptosis.....
so a bit confusing....
would u plz explain mr. addicudo...
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| new_n_lost
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a) decreased bcl2 expression. ???
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| Luckyall
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just a wildguessing... Ac anteroseptal MI is due to LAD ischemia and there is apoptosis involved in "cell death in ischemia and reperfusion". Preventing apoptosis may be a potential therapeuthic target limiting repefusion injury.
So im guesing A
Edited by Luckyall on 05/29/07 - 01:44 AM
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| Addicudo
Forum Guru
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A) NNL and Luckyall ...  it is .. !!! After MI the NORMAL MYOCARDIUM .. would should ... Decreased bcl-2 expression .... as it inhibits apooptosis ... On the other hand the affected myocardium would show .... Increased Bad which is Pro-apoptoic .. !
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| new_n_lost
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One Questions 2 Actually Where is this Q from and can u plz Tells us more abt BAD expression cos i cant seem to find it.
Thnx
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| whournameiz
Forum Senior
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this question is from an actual exam, why would there be less Bcl2 in the normal tissue?? wouldnt there be more in the Normal tissue since it is anti-apoptotic since we dont want the cells to apoptose??
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