new_n_lost
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All the following are characteristics of both MHC class I and class II molecules except:
A) They are expressed codominantly.
B) They are expressed constitutively on all nucleated cells.
C) They are glycosylated polypeptides with domain structure.
D) They are involved in presentation of antigen fragments to T cells.
E) They are expressed on the surface membrane of B cells.
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E) They are expressed on the surface membrane of B cells.
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B
MHC class I molecules are expressed on nearly all nucleated cells, but the constitutive expression of MHC class II molecules is more limited (B cells, dendritic cells, and thymic epithelial cells). MHC class II expression can be induced on other cell types (such as macrophages, endothelial cells, and human T cells) by cytokines.
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