new_n_lost
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CD40 Ligand (CD154) is expressed by which of the following?
A) B cells
B) dendritic cells
C) resting T cells
D) activated T cells
E) all leukocytes
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| Addicudo
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A) B cells
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| tompat
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d
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| drduck
Forum Guru
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i wonder....
CD40 recetors are present on B lymphocyes...but,
CD 40 L, that is CD 40 Ligand is situated on naive T cells...
this what i remember,
can some one express in better way....
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| mytime
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Yeah i was thinking it C too.....will see! 
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| new_n_lost
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Tyrants and Occupiers of territories tend to think, act and feel alike "never argue with a fool, they'll bring you down to their level and beat you with experience" FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."
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| new_n_lost
Forum Hero
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D
CD40 ligand (CD154) is expressed on the surface of the CD4 + T cells as a consequence of the activation that follows the binding of peptide + MHC class II to the TCR.
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Tyrants and Occupiers of territories tend to think, act and feel alike "never argue with a fool, they'll bring you down to their level and beat you with experience" FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."
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| epica
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What about CD40?
On B or T cells?
Also were CD 28?
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| drduck
Forum Guru
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naive cells are activated T cells not resting ones....
mytime got me wrong....
i didnt say answer was C...
it was D....
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| drduck
Forum Guru
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and i feel CD 40 is on B cells while CD 40L on naive T cells.
NNL, plz clear this doubt also....
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| unique1
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Yup, CD 40 is on B cells and CD40 ligand (CD154 ) on the activated T cells. CD40 binds to CD154 and is critical for B cell maturation and secretion of IgG, IgA or IgE . Patients with mutations of CD154 make predominantly IgM and have an immunodeficiency called X-linked hyper-IgM syndrome.
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| unique1
PathoItIs!
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Epica , CD28 is expressed on T-cells and it is a receptor for co-stimulatory molecule B7.
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| epica
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dr.duck, unigue 1, u r Right.
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