Enjoy it :)

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Enjoy it :)

Author

13 Posts

Luckyall
Forum Guru

Topics: 11
Posts: 592

05/25/07 - 04:23 PM

Whas this ?
Where is the pathology?
Enjoy it !

Aldosterone secretion down, pt is hypertensive, yet no enzyme deficiency in zona glomerulosa path.
raised eyebrow

RayBerg
Forum Senior

Topics: 32
Posts: 150

05/25/07 - 04:28 PM

Is this pheochromocytoma? 'cos of inc Epi and NE --> HTN. Also, inhibits renin release which stimulates Aldosterone production via ATII.

Tumor of neurosecretory chromaffin cells.

RayBerg
Forum Senior

Topics: 32
Posts: 150

05/25/07 - 04:28 PM

And no, I didn't enjoy it. wink

silver
Forum Guru
avatar

Topics: 21
Posts: 771

05/25/07 - 08:08 PM

what happened to that scenario? smiling face

___________________
Every disaster hides an opportunity.

Luckyall
Forum Guru

Topics: 11
Posts: 592

05/25/07 - 09:11 PM

why dont you enjoy this one now ? raised eyebrow

Any other thoughts ?

RayBerg
Forum Senior

Topics: 32
Posts: 150

05/25/07 - 09:26 PM

I'm sorry lucky..what was the right answer to your scenario?

Luckyall
Forum Guru

Topics: 11
Posts: 592

05/25/07 - 10:53 PM

any other thoughts ?

RayBerg
Forum Senior

Topics: 32
Posts: 150

05/26/07 - 12:48 AM

Can't really think of anything else. Give me a hint!

RayBerg
Forum Senior

Topics: 32
Posts: 150

05/26/07 - 12:48 AM

RayBerg wrote:
Can't really think of anything else. Give me a hint! Btw..is the reasoning in pheochromocytoma correct?

Luckyall
Forum Guru

Topics: 11
Posts: 592

05/26/07 - 01:06 AM

#10

okay... is an enzyme deficiency... but do get it under this scenario as well, bc most of time BUZZWORDS are not there raised eyebrow

lets try it now

me007
Forum Guru

Topics: 72
Posts: 803

05/26/07 - 10:49 AM

#11

17-hydroxylase def?

Luckyall
Forum Guru

Topics: 11
Posts: 592

05/26/07 - 11:44 AM

#12

Good job me007 ! wink

Excellent and do remember this wild scenario !!!

Luckyall
Forum Guru

Topics: 11
Posts: 592

05/26/07 - 11:52 AM

#13

17 hydroxylase enzyme NOT expressed in Z glomerulosa, only expressed in Z fascic, retic---> Cortisol down, Androgens down----> incr ACTh---> adrenal hyperplasia and incr in all products before blockade----> incr 11 DeoxyCorticosterone= weak mineralocorticoid ( im sure you guys love this 11 DeoxyCorticosterone by now grin

) --> this is responsible for HTN---> decr Renin--->decr AII---> wich is the main stimulus for Z glomerulosa----> therefore Aldosterone secr DOWN

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