doyoudig
Forum Guru
Topics: 144
Posts: 613
|
How does Intubation help a COPD pt maintin O2 exchange vs. giving hime 100% O2 by nasal cannula wich may remove his respiratory drive
Could somone pls give me a good explanation on how (physiology) the resp. drive will decrease by giving 100%O2 in a COPD pt and why intubation is the better choice n what iintubation does excatly
thx much
|
| NE
Forum Guru
Topics: 53
Posts: 504
|
In COPD the respiratory drive is not PaCO2 but PaO2; giving the patient O2 (FiO2= 1) you will decrease his respiratory stimulus----he will not breath anymore because even is CO2 is high, his O2 is high also so "his respiratory center think - I did my job now I can relax!"...
|
| doyoudig
Forum Guru
Topics: 144
Posts: 613
|
does it also have somthing to do with blood vessels constriction in the brain?
and also how does Intubation work better in these pts here?
|
| doyoudig
Forum Guru
Topics: 144
Posts: 613
|
guys don;t remeber the physiology pls explain if you have a minute
also about intubation, thx muxh
|
| ssrpk
Forum Fanatic
Topics: 154
Posts: 2,819
|
first of all, 100% oxygen in never used for prolonged perod of time because oxygen toxicity.
the commonly used oxygen in these settings is 26% or 28% (low conc.) or 60%(high conc.) again, high conc. are used for short period of time!
and in terms of acute exacerbation of respiratory failure intubation needs to be done [not in stable pts] because need for IPPV may arise, however PPV can also be provided via nasal mask...
As for resp. drive, Low PaO2 is the dominant respiratory drive [respiratory centres are not adaptable to low PO2 unlike PCO2 conc.], and therefore raising PaO2 quickly can abolish this drive because respiratory centres are in an adapted state for chronically high levels of PCO2, and PCO2 level in this instance will not stimulate respiration.
___________________
life is guud
|
|
| |
| | | | | |
