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Kaplan Qbank USMLE



Author6 Posts
  #1

54 y/o man with bone pain a year after ileal resection. bone xray shows osteomalacia. what's his concentrations of calcium, 25-OH vit D, and phosphate?

answer: decreased calcium, decreased 25OH vit D, decreased phosphate

my question is why is calcium decreased? since what's going on is secondary hyperPTH, wouldn't serum levels of calcium be increased due to the PTH being released and the bone resorption?

i always get hormone questions wrong b/c i don't know at what point we're supposed to interpret the hormone levels. the question did not make any other specifications on time except that the bone pain appeared a year after the resection.

can someone tell me why calcium is decreased and not increased??



  #2

Hi there!

small intestine is the place where Vit D is absorbed.VitD in turn is essential for calcium absorption.Resection reduces the surface area for vit D uptake and this leads to low Ca.

Hope u got it!

GL


  #3

if the ileum is resected, then the calcium can't be absorbed so calcium decreased


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Everything turns out ok in the end. If it's not ok, then it's not the end.

  #4

but the patient has bone pain from the high PTH, wouldn't the calcium resorbed from the bone make the levels increased?

  #5

obvoiusly bone resolution process is not sufficient enough to raise the Ca++ level upto its normal range, thus drives the PTH higher, don't forget that bone has other functions too rather than being a reservoir only for Ca++.
but certainly overtime osteopenia ensues if the balance is more in the favour of bone resolution

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  #6

agree with ssrpk!

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