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Kaplan Qbank USMLE



Author4 Posts
  #1

23 yo female has skin blistering that results from point mutation in a single gene. epidermal cells in these patients become fragile and rupture. which of the following is the most likel effect of the genetic mutation?

A - defective transport of vesicles from the centrosome to the cell membrane

B - disrupted assembly of keratin into intermediate filaments

C - lack of GTP required to form polymers of tubulin

D - phosphorylation of actin monomers to promote polymerization



thanks! smiling face


  #2

B, epidermolysis bullosa

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  #3

B - disrupted assembly of keratin into intermediate filaments

  #4

B







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