edie
I can, and I will.
Topics: 26
Posts: 1,202
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I understand, Gly, my parents are getting older, they live far away, I hardly get to see them, and miss them terribly. But they both know what is going on with me right now, and are supportive still. It is their love and support, albeit from afar, that I feel most. I am sure if you talked to your folks, you will feel better.
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| glycogen
Forum Senior
Topics: 5
Posts: 134
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thanx edie u r too sweet...thanx for being kind n taking time to write to me..
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| edie
I can, and I will.
Topics: 26
Posts: 1,202
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You are very welcome, Gly, just know that as long as we are alive, life has a way of getting in the way 
Ok, so I am a crappy poet AND a crappy philosopher Can't win them all  GL to you, Gly 
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| dartikaz
Forum Newbie
Topics: 2
Posts: 39
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Hey edie.. Keep going girl! Thanks a lot for your wishes.. I have gone through your posts and they are really inspiring. I like your organized attitude! Wish I can have even 10% of it!!
well... yeah one more thing I have the same prob of forgetting the things that I got done some time back so gonna try the notecard method for pharma... as thats the one I am gonna start up with today (My worst sub since med school)! Lets see how it goes.
Good luck
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| acintya
FOCUS on your Goal!
Topics: 7
Posts: 761
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Don't worry I am sure your NBME will say "Go get'em Edie"!!!
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Life is a Mind Game! Remember, obstacles aren't meant to prevent your success; they only slow you down and show you where you must work harder.
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| edie
I can, and I will.
Topics: 26
Posts: 1,202
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Thank you for stopping by Dartikaz, and your Tweety with Attitude, love it Gotta love notecards, a pain to make, but they do help a lot!
Thanks, I hope so, Acintya.
Studying pharma wears me down like nothing else, not even immuno  Don't mean to be whiny, but it's like that for me now. Need mental viagra, now!!!
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| P4a99
Forum Fanatic
Topics: 44
Posts: 2,430
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excuse me
i just wante to know what they mean by "de novo" ... i read that it means over again but i dont feel that that fits in with the context ...
"..... but some cholesterol may be synthesized de novo. Most de novo synthesis occures in the liver,..."
and on the same page "... lovastatin and simvastatin inhibit de novo cholesterol synthesis..."
So, what do you think?
A;
wikipedia:
In Biochemistry, de novo synthesis refers to the synthesis of complex molecules from simple molecules such as sugars or amino acids, as opposed to their being recycled after partial degradation. For example, de novo synthesis of nucleotides, as opposed to the salvage pathway.
In Medicine and genetics a de novo mutation is one which neither parent possessed nor transmitted. It first appeared in the DNA of the affected individual.
------------------------------------------------------------------------- -------------------------------
Do you know what causes primary hyper lipidemia type IIa? it says in the table page 218 that it is an autosomal dominant disease ... but what is the exact thing that is deficient?
Edited by praying4a99 on 06/20/07 - 09:19 PM
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| edie
I can, and I will.
Topics: 26
Posts: 1,202
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I think it means when it is made up in liver without going through the complex synthesis pathway. So those drugs block this way of making cholesterol in liver?
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| edie
I can, and I will.
Topics: 26
Posts: 1,202
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Type IIa, you have fewer LDL receptors. Those help carry the cholesterol to liver, so if decreased, more cholesterol in blood.
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| P4a99
Forum Fanatic
Topics: 44
Posts: 2,430
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edie wrote:
Type IIa, you have fewer LDL receptors. Those help carry the cholesterol to liver, so if decreased, more cholesterol in blood.
ya ya ya .... and LDL receptor = apoB100 receptor
thanks
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2008 Step 1 Study Plan Discussion ..... I am a moderator not a source for download links. Please do not ask me for any.
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| edie
I can, and I will.
Topics: 26
Posts: 1,202
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Oh yeah, apob100 receptor, I forgot that, thank you, p4a99
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| keepgoing
Forum Fanatic
Topics: 104
Posts: 2,236
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hi edie?whats up??hmm going discussion here..good keep it up gals!!!!!
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| acintya
FOCUS on your Goal!
Topics: 7
Posts: 761
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Building on what Edie explained,de novo synthesis means made from scratch, as opposed to reclaiming it from salvage pathways. I think I remember it in Kaplan lecture someplace.
Great to discuss here! Good luck!
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Life is a Mind Game! Remember, obstacles aren't meant to prevent your success; they only slow you down and show you where you must work harder.
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| edie
I can, and I will.
Topics: 26
Posts: 1,202
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Hello!!!
Yes, KG, it was good to get back to a couple biochem concepts. Thanks, P4a99
Thanks, ACT, your explanation right on the money
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| edie
I can, and I will.
Topics: 26
Posts: 1,202
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Good morning Journal!
There's nothing like starting the day off with Qbank pharma q's. Dismal, only 15 of 23 correct, results at 65%. Below target! So for today, more reading from FA, notecards and charts. Then more q's. Have to do better in pharma, or else 
Updates:
Week 6
Blood/Lymph + FA
6/18: FA virology, hematology; UW q's random: 64%; RR Path Chapts 12 & 13
6/19: FA hematology, pharma
6/20: FA pharma; Qbank heme/gen principles pharma Q's: 65%
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| keepgoing
Forum Fanatic
Topics: 104
Posts: 2,236
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goodmorning edie yang..!!!all the best for week 6 nice plan
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"You must feel confident enough within urself to follow your own dreams"If you think you can, you can.If you think you can't, you're right"
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| glycogen
Forum Senior
Topics: 5
Posts: 134
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good morning edie how r u doin with pharm....it was good to talk to u yesterday..i feel so good that i have ppl to talk out my heart in this forum..happy studying
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| edie
I can, and I will.
Topics: 26
Posts: 1,202
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Hi KG, thanks for the looking out
Well, just finished PreTest pharm q's, and of 69, only got 42 correct  for a whopping score of 61%. I predict below avg performance in pharm on my upcoming NBME!
On a lighter note, my darling dear husband, who had it up to his eyeballs with my new wallpaper/study charts, went out to Staples and brought back 2 large dry-erase boards and a big pack of dry erase markers for me, in exchange for taking down all of the charts. Half of my study is his office, and yes, my stuff sort of spilled over to his side, no idea how that happened  It actually worked out great, room looks neater, everyone's happy I hole-punched my charts and stuck them in a binder with other notes I refer to often, and feel better about moving on with pharm. Going to go ahead, bite the bullet and read the 30+ pages (not including the mcq's) in baby Katzung pharm book on antibiotics, then do more q's later on.
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| P4a99
Forum Fanatic
Topics: 44
Posts: 2,430
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Hi, i have the Q-book & pretest ... when do you think its better for me to start doing their Qs? and do i do them as a test or just for learning more things and looking at the facts in a new way?
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| edie
I can, and I will.
Topics: 26
Posts: 1,202
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Hi! You can do a few, say, 10-20 q's before you read as a pretest, next do a set after reading for learning/reinforcing concepts, then another set later for testing yourself. I think it's good to have access to as many diff types of Q's possible so you can be prepared for whatever MLE throws your way.
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| P4a99
Forum Fanatic
Topics: 44
Posts: 2,430
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thanks ...
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| ShweHope99.9998
Forum Fanatic
Topics: 12
Posts: 2,716
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Hi Ed,
Good idea re all note sheet down to file from the wall . Well me, do notes with some flash card , display on my study desk at , near another LCD .
Hubby though , me too busy not able to clean up so he stack them in one pile.
Oh well , after weeks, month. i also need to move on another topics , so I just leave it like that, after try to put up again, got clean up again, even I told him the purpose of spreading all card at every eye cornor of my study space , imagine
Any way, as I said , back on Wed now, so far so good . Will claim Sat too for study, he is working , he he .
Ed, how is RR bioch ??
Good, need to buy or not ??
How is Robin R., no found?? Let me know if still need it .
GL GL GL happy success study to us, all
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| medocuk
IM-RES
Topics: 26
Posts: 1,466
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A whole new page and I am no where in sight.What is thisssssssssssss????
Ok so when is the NBME.. keep me posted.Good luck with your review..
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| ShweHope99.9998
Forum Fanatic
Topics: 12
Posts: 2,716
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She said will do NBME on Sunday
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