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Kaplan Qbank USMLE



Author5 Posts
  #1

Why not what I wrote .. wink !!

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  #2

C.PTU

I think this patient was taking PTU for tx of hyperthyroidism.

The dosage of propylthiouracil during treatment of hyperthyroidism in pregnancy must be kept to the minimum necessary for control of the disease (ie, < 300 mg daily), because it may affect the function of the fetal thyroid gland. Methimazole is a potential alternative, although there is concern about a possible risk of fetal scalp
defects.


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  #3

But .. I went tthe other way .. I thought that the pt might have had HYPOthyroid .. and would have been taking T4 for thta purpose .. and thus .. the fetus .. has had a badly developed thyroid .. (atrophy) .. and thus after birth .. increased TSH .. but NO T4 .. so i opted for T4 as the answer ... !! so .. where did I go wrong .. ? Or someone else .. raised eyebrow

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... Idle hands are the DeVilS play ground ...

  #4

mmmm no doubt is PTU or Propranol.raised eyebrow
PTU is DOC in patients with hyperthyroidism during pregnancy---> so mommy most likely has been Hyper.
PTU--->Taper gradually to minimum dose required to keep patient clinically euthyroid and to avoid fetal hypothyroidism !!!!!!!!!!!!!! So if anything i d say they didnt taper the PTU dose while mommy's been pregnantsmiling face bc PTU crosses the placenta but is said to be safe in pregn( extensively prot bound---> free fract of PTU lower-->drug doesnt readily cross placenta barrier).
On the other hand, PROPRAN.--->Safety for use during pregnancy has not been established:eyebrow
I would still opt for PTU , atleast bc everytime when i overlook any Qs im most likely to get it wrong

  #5

C.PTU



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