kiranmayi
Forum Guru
Topics: 237
Posts: 407
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what is the treatment for prostatic hypertrophy
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| dxtxpx
Forum Guru
Topics: 259
Posts: 1,233
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alpha blockers(prazosin and terazosin), 5 alpha reducatse inhibitors (finasteride), anticholinergic (propantheline bromide), TCA (amitriptyline)
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| usmleasr
Forum Guru
Topics: 105
Posts: 970
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how does anticholinergics help??parasympathetic promote emptying right?? :roll:
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| asmi
Forum Hero
Topics: 1043
Posts: 4,609
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here is the answer :
These drugs are not used for obstruction due to BPH, but rather for bladder instability (frequency, urgency) which may mimic or coexist with BPH.
Anticholinergics such as propantheline bromide or tricyclic antidepressants with anticholinergic effects such as imipramine, nortriptyline and amitriptyline are occasionally used where there are severe irritative symptoms but few obstructive symptoms. These drugs should only be considered after a urodynamic assessment which confirms bladder instability and excludes significant obstruction. The patients must be warned that the drugs can precipitate retention.
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