Mikeland
Forum Senior
Topics: 24
Posts: 109
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A 7-year-old girl contracts chicken pox from her sister. Five days after the onset of the
rash, she begins vomiting and becomes lethargic. She is seen in the emergency room, and
admitted to the hospital, after which she becomes comatose. Laboratory examination is
significant for elevated liver enzymes and ammonia. Which of the following is the most
likely diagnosis?
A. Crigler-Najjar syndrome
B. Dubin-Johnson syndrome
C. Gilbert syndrome
D. Reye syndrome
E. Rotor syndrome
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| titly
Forum Elite
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Posts: 290
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D. reyes syndrome. bt no hist of aspirin ingestion is stated.
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| Mikeland
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Posts: 109
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| Medusin
Forum Elite
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Posts: 279
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I guess you just have to assume she was given aspirin...Besides all other options have to do with hyperbilirubinemias...so by process of elimination I guess thats the only answer...
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| Mikeland
Forum Senior
Topics: 24
Posts: 109
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Hi, Medusin, "Aspirin use has been linked to the development of this
disorder, but cases occur in the absence of salicylate ingestion".
"Reye syndrome (fatty liver with encephalopathy) is an acute (and
potentially fatal) post-viral injury that is characterized by severe mitochondrial damage affecting the liver, brain, skeletal muscle, heart, and kidneys. Most patients are children,
although adult cases have been described. Varicella and influenza A and B are the most common precipitating illnesses. Aspirin use has been linked to the development of this disorder, but cases occur in the absence of salicylate ingestion".
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| Medusin
Forum Elite
Topics: 17
Posts: 279
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WOW! I did not knwo that!!!
Thanks Mike! Could you tell us your reference please?
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| Mikeland
Forum Senior
Topics: 24
Posts: 109
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Kaplan Q bank
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