sprint123
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Kaplan Qbook Question says an ASYMPTOMATIC individual with Increased PTH levels,po4-2.5,ALP 50.NSIM??
A.oral fluids
B.Bisphosphonates.
Please explain the answer
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| Luckyall
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Bisphosphonates stabilize hydroxyapatite bone structure& induce osteoblasts to secrete inhibitors of osteoclasts---> decr bone resorbtion
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| vradojc1
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Treatment depends upon age and Ca2+ level.
Surgery mandatory if:
Ca >1.0 above upper normal level
age<50
24h urinary Ca >400
Creatinine clearance reduced >30%
Bone mineral density - T < -2.5
Otherwise medical treatment, starting with hydration to prevent nephrolithiasis.
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| sprint123
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Posts: 870
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Answer given was oral fluids--------Why can't it be bisphosphonates??Any idea....?
Age of the patient is 60 and urinary calcium is within normal limits
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| Luckyall
Forum Guru
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i guess hydration is a better option..correct... biphosph---ussualy given for postmenop. osteoporosis
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| vradojc1
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So you have no signs of bone disease, PO4 is at lower normal end, no hypercalciuria...why do you want to expose a patient to SE of a drug if there is no need for it?
Just hydrate them and that's it. If they were having severe symptoms, then bisphosphonates would kick in. Otherwise, keep simple as possible!
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| sprint123
Forum Guru
Topics: 129
Posts: 870
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Thanks lucky and vrad!
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