dxtxpx
Forum Guru
Topics: 259
Posts: 1,233
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How does virus gets resistance to acyclovir?
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| kiranmayi
Forum Guru
Topics: 237
Posts: 407
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alteration in viral drug activator herpes simplex thymidine kinase
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| dxtxpx
Forum Guru
Topics: 259
Posts: 1,233
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yes and what else
there are total of three points in acyclovir resistance
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| kiranmayi
Forum Guru
Topics: 237
Posts: 407
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If viral DNA polymerase mutates
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| dxtxpx
Forum Guru
Topics: 259
Posts: 1,233
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1) Viral mutants without any thymidilate kinase
2) Mutants have kinase, but kinase wont phosphorylate acyclovir
3) Alterations in DNA polymerase so that it wont bind triphosphate
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| usmleasr
Forum Guru
Topics: 105
Posts: 970
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