Mikeland
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A 6 month-old child is evaluated by a pediatrician for growth failure and particularly foul smelling stools. Studies demostrate an elevated sweat chloride concentration. The child is placed on oral enzyme supplementation aond begins to grow. Whihc of the following is a characteristic of the defective protein on this individual?
A Binds ATP
B Binds G-protein
C Enters the nucleus
D has kinase activity
E Is a cationic channel.
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| po
Forum Elite
Topics: 39
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was going for E[ion channel],but after searching...it is A.
Yes,good q.
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| po
Forum Elite
Topics: 39
Posts: 356
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Structurally, CFTR is a type of gene known as an ABC gene.[6] Its protein possesses two ATP-hydrolyzing domains which allows the protein to use energy in the form of ATP. It also contains two domains comprised of 6 alpha helices apiece which allow the protein to cross the cell membrane. A regulatory binding site on the protein allows activation by phosphorylation, mainly by cAMP-dependent protein kinase.[6] The carboxyl terminal of the protein is anchored to the cytoskeleton by a PDZ domain interaction.[34]
http://en.wikipedia.org/wiki/Cystic_fibrosis#Mole...
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| Mikeland
Forum Senior
Topics: 24
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bang, correct
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| afrocaribb
Forum Senior
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wow! i didnt know that , good question!
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